I recently had a problem when setting up a new WordPress development environment on my local PC. The installation went fine. I selected Permalinks. I manually updated the .HTACCESS file to include “Options +FollowSymlinks”. I did the normal things and Permalinks just wouldn’t work. The problem ended up being that the “rewrite_module” in Apache was not enabled. I used Webmin to go into the list of Apache Modules and enable the “rewrite_module” and all is good now.